Table 1.
Characteristics of the study population
| Total (n = 126) | Men (n = 58) | Women (n = 68) | P a | |
| Age, years | 63.6 ± 10.1 | 64.2 ± 10.0 | 63.2 ± 10.3 | 0.58 |
| Height, cm | 167.7 ± 9.1 | 174.6 ± 6.8 | 161.8 ± 6.1 | <0.001 |
| Weight, kg | 81.4 ± 15.5 | 85.1 ± 14.9 | 78.3 ± 15.3 | 0.01 |
| BMI, kg/m2 | 28.9 ± 5.1 | 27.8 ± 3.8 | 29.9 ± 5.8 | 0.02 |
| WOMAC score | 436 ± 224 | 411 ± 214 | 457 ± 232 | 0.25 |
| SF-36 score | 98 ± 7 | 98 ± 6 | 99 ± 8 | 0.25 |
| Physical activity | 6.2 ± 1.8 | 6.7 ± 1.7 | 5.8 ± 1.8 | 0.01 |
| Time between scans, years | 1.95 ± 0.21 | 1.94 ± 0.19 | 1.96 ± 0.23 | 0.58 |
| OA gradeb | ||||
| Grade of medial osteophytes | ||||
| <2 | 107 | 50 | 57 | 0.50 |
| ≥ 2 | 18 | 7 | 11 | 0.35 |
| Grade of medial JSN | ||||
| <2 | 90 | 35 | 55 | 0.04 |
| ≥ 2 | 35 | 22 | 13 | 0.13 |
| Grade of lateral osteophytes | ||||
| <2 | 103 | 48 | 55 | 0.49 |
| ≥ 2 | 22 | 9 | 13 | 0.39 |
| Grade of lateral JSN | ||||
| <2 | 116 | 55 | 61 | 0.58 |
| ≥ 2 | 9 | 2 | 7 | 0.10 |
| Tibial plateau area, mm2 | ||||
| Medial | 2054.6 ± 363.9 | 2331.1 ± 304.3 | 1860.2 ± 263.2 | <0.001 |
| Lateral | 1407.2 ± 256.7 | 1533.4 ± 244.9 | 1328.2 ± 232.8 | <0.001 |
Except where indicated otherwise, values are means ± standard deviations. aMen vs women, by independent t-tests or chi-square test, as appropriate. bValues are the number of subjects in each grade category. One radiograph was lost after the study commenced. BMI, body mass index; JSN, joint-space narrowing.; MRI, magnetic resonance imaging; OA, osteoarthritis; SF-36, 36-Item Short-Form Health Survey; WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index.