Table 2.
Crude analysis | Adjusted analysis | |||||||
Annual change | Total | P | Men | Women | Pa | Men | Women | Pb |
Increase, mm2 | ||||||||
Medial | 36.8 ± 70.7 | <0.001 | 38.3 ± 62.6 | 35.7 ± 76.1 | 0.85 | 70.8 ± 12.3 | 13.5 ± 9.6 | 0.002 |
Lateral | 19.1 ± 60.1 | 0.004 | 16.5 ± 83.9 | 20.4 ± 45.1 | 0.77 | 17.2 ± 13.3 | 20.1 ± 8.5 | 0.87 |
Change % | ||||||||
Medial | 2.2 ± 6.9 | <0.001 | 1.6 ± 2.8 | 2.6 ± 8.7 | 0.49 | 5.4 ± 1.1 | 0.004 ± 0.9 | 0.001 |
Lateral | 1.5 ± 4.3 | 0.004 | 1.3 ± 5.8 | 1.6 ± 3.4 | 0.79 | 1.6 ± 0.9 | 1.5 ± 0.6 | 0.95 |
Values are mean ± standard deviations, or means ± standard errors for adjusted analysis. aMen vs women. bMen vs women, adjusted for age, body mass index, physical activity, grade of osteophytes, grade of joint-space narrowing, and baseline tibial plateau bone area.