Table 2.
Arthritis | OVX | n | Bone marrow cellularity (× 106) | B cells per femur (× 106) | T cells per femur (× 106) | CD4+ cells per femur (× 106) | CD69+/CD4+ cells (%) | CD8+ cells per femur (× 106) | CD69+/CD8+ cells (%) |
- | - | 10 | 5.1 (4.0–6.4) | 1.5 (1.0–1.7)*** | 0.06 (0.05–0.09) | 0.02 (0.02–0.04) | 25 (18–30) | 0.013 (0.008–0.018) | 3 (1–3) |
+ | 10 | 6.0 (5.0–8.6) | 2.4 (2.0–3.0) | 0.05 (0.04–0.07) | 0.02 (0.02–0.03) | 29 (26–31) | 0.008 (0.006–0.012) | 4 (2–6) | |
+ | - | 18 | 5.2 (4.7–7.0) | 1.0 (0.8–1.3)**† | 0.05 (0.04–0.06) | 0.02 (0.01–0.02) | 50 (43–58)***††† | 0.004 (0.002–0.007)††† | 9 (4–25)††† |
+ | 15 | 6.1 (5.3–8.4) | 1.5 (1.0–2.5)† | 0.05 (0.03–0.05) | 0.02 (0.01–0.02) | 35 (29–40) | 0.005 (0.002–0.006)††† | 10 (5–16)† |
Values are medians and interquartile ranges for each group; n is the number of mice. Comparison between sham operation and ovariectomy (OVX): **P < 0.01; ***P < 0.001. Comparison between arthritic mice and their controls: †P < 0.05; †††P < 0.001.