Table 1.
Cytokine-positive cells isolated from the tumour
Experimental group | Sample (days) | Cytokine | ||||
Tumour necrosis factor alpha | Interferon gamma | IL-6 | IL-4 | IL-10 | ||
Tumour control | 18 | 24 ± 2ae | 22 ± 6ac | 29 ± 2a | 25 ± 5a | 18 ± 2ae |
22 | 12 ± 4bcd | 17 ± 3ad | 25 ± 3a | 17 ± 4ad | 6 ± 2b | |
27 | 13 ± 1bcd | 12 ± 4b | 23 ± 4abd | 10 ± 3ce | 8 ± 2b | |
P(+) 2d | 18 | 21 ± 3ce | 26 ± 8cde | 12 ± 3d | 11 ± 1bcde | 19 ± 4a |
22 | 9 ± 1d | 10 ± 2b | 8 ± 1cd | 12 ± 2bcde | 7 ± 3bc | |
27 | 11 ± 3bd | 12 ± 4bd | 17 ± 3d | 10 ± 1ce | 9 ± 2bc | |
P(-) 2d | 18 | 14 ± 6bcd | 14 ± 5abd | 10 ± 3c | 7 ± 2e | 9 ± 4bc |
22 | 19 ± 4bce | 13 ± 4ab | 16 ± 1bd | 13 ± 5bcde | 18 ± 6ae | |
27 | 12 ± 2bd | 12 ± 2b | 17 ± 2bd | 7 ± 2e | 8 ± 2bd | |
P(+) 7d | 18 | 22 ± 7ac | 20 ± 2ae | 4 ± 2c | 15 ± 5dbc | 14 ± 3ace |
22 | 31 ± 4a | 30 ± 5c | 9 ± 2c | 8 ± 1e | 29 ± 7 | |
27 | 13 ± 1bcd | 17 ± 5abe | 4 ± 1c | 6 ± 1e | 12 ± 2eb | |
P(-) 7d | 18 | 12 ± 2bcd | 14 ± 1b | 4 ± 1c | 12 ± 3bcde | 13 ± 6acde |
22 | 53 ± 15 | 44 ± 6 | 17 ± 3bd | 12 ± 3bcde | 16 ± 4ace | |
27 | 11 ± 4bd | 24 ± 5ac | 13 ± 4d | 9 ± 1ce | 9 ± 3bcd |
Results are expressed as means ± standard deviation of cytokine-positive cells for each 100 counted cells (cells/100). Means for each cytokine without a common letter differ significantly (P < 0.05).