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. 2025 Jan 20;31(1):96–104. doi: 10.1038/s41591-024-03341-8

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© The Author(s) 2025

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 1 — a, MRI reconstruction of the participant’s brain with the implant locations depicted as blue squares. Two 96-channel silicon microelectrode arrays were placed in hand ‘knob’ area of left precentral gyrus in 2016. The red line indicates the central sulcus (CS). Panel from Deo et al.⁴¹. b and c, Confusion matrices showing the probability of correctly classifying attempted finger movements using 2 s, b, and 150-ms, c, windows from an offline analysis on open-loop data from day 2423. IM, index-middle; RL, ring-little; TH, thumb.