Table 3.
Phosphorylation sites in various HSP70 members at S, T, and Y residues
| Gene Name | Serine (S) | Threonine (T) | Tyrosine (Y) |
|---|---|---|---|
| HSPA1A | 16, 40, 85, 106, 153, 254, 276, 277, 281, 286, 296, 307, 312, 340, 362, 400, 418, 494, 511, 537, 544, 551, 563, 579, 631 | 13, 38, 45, 47, 66, 111, 125, 145, 158, 211, 265, 273, 275, 278, 298, 313, 341, 425, 430, 450, 491, 495, 502, 585, 636 | 15, 41, 294, 371, 431, 525 |
| HSPA1B | 16, 40, 85, 106, 153, 254, 275, 276, 277, 281, 286, 296, 307, 312, 340, 362, 400, 418, 494, 511, 537, 544, 551, 563, 579, 631 | 13, 38, 45, 47, 66, 111, 125, 145, 158, 211, 265, 273, 278, 298, 313, 341, 425, 430, 450, 491, 495, 502, 585, 636 | 15, 41, 294, 371, 431, 525 |
| HSPA1L | 18, 42, 108, 155, 241, 256, 277, 278, 279, 288, 298, 387, 402, 420, 513, 546, 556, 565, 567, 581 | 15, 40, 47, 49, 68, 127, 147, 160, 213, 267, 275, 280, 300, 315, 343, 364, 427, 432, 452, 493, 497, 504, 618, 624, 636 | 17, 43, 290, 296, 342, 373, 433, 527, 626 |
| HSPA2 | 17, 41, 97, 154, 242, 278, 279, 280, 284, 289, 299, 343, 365, 403, 497, 514, 530, 547, 622, 630 | 14, 39, 46, 48, 65, 67, 112, 126, 146, 159, 164, 214, 268, 276, 281, 301, 316, 344, 414, 421, 428, 430, 433, 453, 498, 505, 555, 634 | 16, 42, 291, 297, 374, 434, 528, 550, 595, 614 |
| HSPA4 | 31, 40, 47, 54, 58, 76, 123, 131, 155, 258, 267, 287, 298, 323, 355, 384, 393, 403, 408, 414, 415, 448, 463, 471, 474, 475, 476, 491, 496, 503, 546, 552, 556, 575, 633, 641, 647, 692, 714, 715, 737, 756, 765, 777, 784, 828, 830 | 35, 63, 99, 104, 114, 149, 160, 225, 230, 300, 328, 364, 433, 468, 512, 538, 576, 649, 655, 732, 738, 776, 824 | 14, 89, 148, 336, 446, 454, 597, 624, 626, 660, 671, 723 |
| HSPA5 | 4, 40, 64, 86, 300, 301, 311, 319, 354, 365, 406, 448, 452, 448, 452, 567, 571, 587, 588, 607, 632, 637 | 37, 69, 91, 124, 137, 151, 156, 166, 171, 184, 274, 321, 323, 338, 366, 428, 441, 445, 462, 473, 481, 518, 525, 527, 534, 561, 593, 643, 648 | 39, 65, 127, 396, 568 |
| HSPA6 | 18, 42, 59, 87, 98, 127, 155, 213, 256, 277, 278, 279, 288, 298, 309, 314, 342, 364, 402, 489, 496, 513, 543, 554, 559, 634 | 15, 40, 47, 49, 68, 83, 115, 132, 147, 160, 267, 275, 280, 300, 315, 343, 414, 427, 429, 432, 452, 493, 497, 504, 626 | 17, 43, 296, 373, 433, 527, 594 |
| HSPA7 | 18, 42, 59, 87, 98, 127, 155, 213, 256, 277, 278, 279, 288, 298, 309, 314 | 15, 40, 47, 49, 68, 83, 115, 132, 147, 150, 160, 267, 275, 280, 300, 315 | 17, 43, 296 |
| HSPA8 | 16, 40, 85, 113, 121, 153, 275, 276, 277, 281, 286, 296, 329, 340, 362, 381, 385, 400, 489, 494, 511, 537, 538, 541, 544, 613, 633, 637, 638 | 13, 38, 45, 47, 64, 66, 111, 125, 140, 145, 158, 211, 265, 273, 278, 298, 313, 341, 418, 425, 427, 430, 450, 495, 502, 552, 641 | 15, 41, 288, 294, 371, 431, 525, 545, 611 |
| HSPA9 | 3, 29, 34, 42, 48, 89, 148, 162, 164, 200, 253, 320, 321, 322, 337, 376, 378, 408, 444, 469, 473, 533, 550, 554, 627, 638, 639, 644, 657, 662, 664, 665, 667 | 22, 62, 87, 111, 116, 120, 177, 185, 192, 205, 294, 347, 356, 362, 449, 462, 466, 504, 539, 592, 594 | 46, 118, 568, 652 |
| HSPA12A | 9, 19, 23, 27, 37, 39, 47, 50, 68, 73, 190, 195, 226, 243, 258, 259, 267, 289, 303, 316, 348, 388, 408, 420, 428, 436, 437, 444, 458, 533, 587, 594, 605, 611, 632, 663, 665 | 18, 34, 45, 66, 99, 101, 106, 146, 150, 202, 277, 291, 320, 324, 474, 513, 536, 589, 614, 623, 631, 644, 651, 662 | 21, 122, 311, 339, 346, 360 |
| HSPA12B | 16, 17, 21, 25, 29, 44, 46, 58, 60, 72, 77, 80, 149, 192, 194, 230, 247, 262, 276, 279, 280, 291, 294, 347, 409, 413, 433, 434, 442, 449, 492, 539, 583, 593, 631, 672, 676, 680 | 32, 42, 70, 103, 110, 121, 200, 206, 296, 339, 375, 397, 428, 542, 662, 673 | 126, 316, 344, 351 |
| HSPA13 | 10, 44, 69, 72, 84, 113, 136, 143, 185, 249, 280, 323, 324, 334, 335, 343, 350, 354, 357, 366, 429 | 6, 30, 40, 41, 52, 95, 108, 135, 274, 312, 372, 379, 428 | 42, 79, 97, 146, 162, 272 |
| HSPA14 | 42, 55, 61, 74, 75, 122, 130, 174, 186, 202, 204, 206, 219, 241, 246, 264, 271, 273, 277, 284, 305, 338, 389, 407, 418, 435, 451, 487, 504 | 35, 63, 104, 108, 127, 188, 234, 274, 413, 420, 481, 491, 493, 497 | 444 |