Table 4. Analysis of differences in DTI metrics between patients A with severe and non-severe foot drop and B who did and did not recover.

A. DTI and foot drop severity
	Recovered (mean (SD))	Not recovered (mean (SD))	P value
FA	0.40 (0.06)	0.48 (0.05)	0.04
RD (10−3 mm2/s)	0.91 (0.20)	0.94 (0.15)	0.72
AD (10−3 mm2/s)	1.75 (0.29)	2.09 (0.17)	0.20
MD (10−3 mm2/s)	1.19 (0.22)	1.32 (0.17)	0.73

B. DTI and foot drop recovery
	Foot drop MRC≤3/5 (mean (SD))	Foot drop MRC 4/5 (mean (SD))	P value
FA	0.42 (0.07)	0.45 (0.06)	0.34
RD (10−3 mm2/s)	0.93 (0.17)	0.82 (0.27)	0.65
AD (10−3 mm2/s)	1.86 (0.31)	1.66 (0.31)	0.75
MD (10−3 mm2/s)	1.24 (0.20)	1.10 (0.29)	0.70

Analysis: Analysis of covariance (ANCOVA) with DTI metrics as dependent covariable and foot drop severity as categorical independent variable. Age, BMI and footedness (dummy variable) were modelled as covariates. Only patients with unilateral disease were included. Patients who underwent surgery were excluded as well from the recovery analysis. Bonferroni corrected.

ADaxial diffusivityBMIbody mass indexDTIdiffusion tensor imagingFAfractional anisotropyMDmean diffusivityRDradial diffusivity