Table 3.
Univariate and Multivariate Logistic Analysis in Patients with GC
| Male | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P value | OR | 95% CI | P value | |
| Age (years) | <0.001 | <0.001 | ||||
| ≤55 | 1 | 1 | ||||
| >55 | 12.051 | 9.143–15.884 | 4.105 | 2.891–5.827 | ||
| CEA (ng/mL) | <0.001 | <0.001 | ||||
| ≤1.87 | 1 | 1 | ||||
| >1.87 | 2.720 | 2.107–3.512 | 1.923 | 1.353–2.735 | ||
| CA19-9 (U/mL) | <0.001 | 0.025 | ||||
| ≤16.55 | 1 | 1 | ||||
| >16.55 | 3.418 | 2.316–5.044 | 1.742 | 1.072–2.830 | ||
| SII | <0.001 | 0.546 | ||||
| ≤462.69 | 1 | 1 | ||||
| >462.69 | 3.310 | 2.476–4.425 | 1.144 | 0.739–1.771 | ||
| PNI | <0.001 | <0.001 | ||||
| ≤55.33 | 1 | 1 | ||||
| >55.33 | 0.036 | 0.025–0.051 | 0.055 | 0.038–0.080 | ||
| SIRI | <0.001 | <0.001 | ||||
| ≤0.77 | 1 | 1 | ||||
| >0.77 | 4.372 | 3.323–5.753 | 2.211 | 1.481–3.302 | ||
| Female | Univariate | Multivariate | ||||
| OR | 95% CI | P value | OR | 95% CI | P value | |
| Age (years) | <0.001 | 0.005 | ||||
| ≤55 | 1 | 1 | ||||
| >55 | 2.927 | 2.119–4.043 | 1.855 | 1.203–2.858 | ||
| CEA (ng/mL) | <0.001 | <0.001 | ||||
| ≤2.04 | 1 | 1 | ||||
| >2.04 | 3.219 | 2.287–4.531 | 2.576 | 1.634–4.062 | ||
| SII | <0.001 | 0.038 | ||||
| ≤504.32 | 1 | 1 | ||||
| >504.32 | 3.566 | 2.450–5.193 | 1.867 | 1.035–3.368 | ||
| PNI | <0.001 | <0.001 | ||||
| ≤54.18 | 1 | 1 | ||||
| >54.18 | 0.046 | 0.031–0.069 | 0.058 | 0.038–0.089 | ||
| SIRI | <0.001 | 0.023 | ||||
| ≤0.79 | 1 | 1 | ||||
| >0.79 | 3.737 | 2.592–5.389 | 1.934 | 1.095–3.416 | ||
Abbreviations: CEA, carcinoembryonic antigen; CA19-9, carbohydrate antigen 19–9; PNI, prognostic nutritional index; SII, systemic immune-inflammation index; SIRI, the systemic inflammation response index; OR, odds ratio; CI, confidence interval.