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(A) Structures of dopachrome methyl ester (1), a chromogenic substrate for the measurement of MIF enzymatic activity, and its tautomerized, colorless product (2). (B) Structures of acetaminophen (3) and the oxidation products N-acetyl-p-benzoquinone imine (NAPQI, 4) and N-acetyl-3-hydroxy-p-benzoquinone imine (HQ, 6), which are related structurally to 1.
