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. 2025 Jan 7;15:1517968. doi: 10.3389/fimmu.2024.1517968

Table 2.

The difference between low and high ISS before and after IPTW.

Characteristic Before IPTW P-value After IPTW P-value
Low ISS High ISS Low ISS High ISS
n=249 n=148 n=392 n=404
Sex 0.076 0.957
Female 70 (28.1%) 29 (19.6%) 98.7 (25.2%) 100.8 (24.9%)
Male 179 (71.9%) 119 (80.4%) 292.9 (74.8%) 303.5 (75.1%)
Age 0.899 0.918
≤65 204 (81.9%) 122 (82.4%) 322.2 (82.3%) 334.3 (82.7%)
>65 45 (18.1%) 26 (17.6%) 69.5 (17.7%) 69.9 (17.3%)
BMI (kg/m2) 0.117 0.976
≤18.5 29 (11.6%) 14 (9.5%) 41.4 (10.6%) 44.1 (10.9%)
18.5-25 183 (73.5%) 100 (67.6%) 282.4 (72.1%) 293.6 (72.6%)
≥25 37 (14.9%) 34 (23.0%) 67.8 (17.3%) 66.6 (16.5%)
Histologic grade 0.214 0.984
Gx/G1 96 (38.6%) 68 (45.9%) 160.0 (40.8%) 163.0 (40.3%)
G2 137 (55.0%) 68 (45.9%) 204.3 (52.2%) 211.1 (52.2%)
G3 16 (6.4%) 12 (8.1%) 27.4 (7.0%) 30.2 (7.5%)
Tumor location 0.018 0.912
Proximal 23 (9.2%) 8(5.4%) 30.7 (7.8%) 36.4 (9.0%)
Mid 168 (67.5%) 87 (58.8%) 256.5 (65.5%) 256.9 (63.5%)
Distal 58 (23.3%) 53 (35.8%) 104.5 (26.7%) 111.0 (27.5%)
T stage 0.279 0.948
T1 69 (27.7%) 29 (19.6%) 97.9 (25.0%) 96.0 (23.7%)
T2 43 (17.3%) 31 (20.9%) 73.0 (18.6%) 84.9 (21.0%)
T3 130 (52.2%) 85 (57.4%) 211.1 (53.9%) 215.4 (53.3%)
T4a 7(2.8%) 3(2.0%)
N stage 0.001 0.999
N0 131 (52.6%) 59 (39.9%) 189.8 (48.5%) 195.0 (48.2%)
N1 72 (28.9%) 37 (25.0%) 110.0 (28.1%) 114.7 (28.4%)
N2 40 (16.1%) 40 (27.0%) 75.6 (19.3%) 76.8 (19.0%)
N3 6(2.4%) 12 (8.1%) 16.3 (4.2%) 17.8 (4.4%)
TNM stage 0.078 1.000
I 62 (24.9%) 32 (21.6%) 94.0 (24.0%) 96.3 (23.8%)
II 82 (32.9%) 36 (24.3%) 117.0 (29.9%) 119.3 (29.5%)
III 98 (39.4%) 71 (48.0%) 163.2 (41.7%) 169.9 (42.0%)
IVA 7(2.8%) 9(6.1%) 17.6 (4.5%) 18.8 (4.7%)
Lymphadenectomy 0.065 0.998
Two-field 210 (84.3%) 113 (76.4%) 319.8 (81.7%) 330.1 (81.7%)
Three-field 39 (15.7%) 35 (23.6%) 71.9 (18.3%) 74.1 (18.3%)
Surgical procedure 0.953 0.959
McKeown 225 (90.4%) 134 (90.5%) 353.4 (90.2%) 365.5 (90.4%)
Ivor Lewis 24 (9.6%) 14 (9.5%) 38.2 (9.8%) 38.8 (9.6%)