Table 2. Inhibitors of EV release or uptake.
Action | Inhibitor | Literature |
---|---|---|
Inhibition of exosome formation | DPTIP (2,6-dimethoxy-4–(5-phenyl-4-thiophen-2-yl-1H-imidazole-2-yl)-phenol) | [154] |
Glyburide | [146] | |
GW4869 | [155] | |
Imipramine | [156] | |
Indomethacin | [157] | |
Simvastatin | [158] | |
Spiroepoxide | [159] | |
Inhibition of exosome formation and release | Ketoconazole | [160] |
Macitentan | [161] | |
Manumycin A | [162] | |
Sulfisoxazole | [163] | |
Tipifarnib | [164] | |
Inhibition of exosome release | Calpeptin | [165] |
DMA (Dimethyl amiloride) | [166] | |
Esomeprazole | [146] | |
Ketotifen | [167] | |
Lansoprazole | [168] | |
Omeprazole | [146] | |
Pantoprazole | [146] | |
Inhibition of exosome/ectosome release | Cannabidiol | [169] |
Inhibition of ectosome release | Bisindolylmaleimide I | [170] |
Calpeptin | [171] | |
Pantethine | [171] | |
U0126 | [172] | |
Y-27632 | [171] | |
Inhibition of exosome/ectosome uptake | Dynasore | [173] |
Methyl-β-cyclodextrin | [146] |