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. 2025 Jan 16;33(2):245–262. doi: 10.32604/or.2024.055449

Table 2. Inhibitors of EV release or uptake.

Action Inhibitor Literature
Inhibition of exosome formation DPTIP (2,6-dimethoxy-4–(5-phenyl-4-thiophen-2-yl-1H-imidazole-2-yl)-phenol) [154]
Glyburide [146]
GW4869 [155]
Imipramine [156]
Indomethacin [157]
Simvastatin [158]
Spiroepoxide [159]
Inhibition of exosome formation and release Ketoconazole [160]
Macitentan [161]
Manumycin A [162]
Sulfisoxazole [163]
Tipifarnib [164]
Inhibition of exosome release Calpeptin [165]
DMA (Dimethyl amiloride) [166]
Esomeprazole [146]
Ketotifen [167]
Lansoprazole [168]
Omeprazole [146]
Pantoprazole [146]
Inhibition of exosome/ectosome release Cannabidiol [169]
Inhibition of ectosome release Bisindolylmaleimide I [170]
Calpeptin [171]
Pantethine [171]
U0126 [172]
Y-27632 [171]
Inhibition of exosome/ectosome uptake Dynasore [173]
Methyl-β-cyclodextrin [146]