Figure 4.

14 μg/mL pyrrocidine A + B in combination nearly eliminates F. verticillioides WT growth. Growth curve analysis of F. verticillioides WT challenged with the following treatment conditions: 0.5% DMSO control; 0.5% DMSO containing pyrrocidine A + B combined at the following final concentrations, (1) 10, (2) 12, (3) 14, (4) 16, (5) 18, and (6) 20 μg/mL, monitored for 120 h, at 28°C, with continuous shaking in the dark in modified Fusarium minimal media. Ten replicates were tested per treatment, and optical density (OD600) measurements were recorded every 30 min. (A) Plot of the raw data. Individual wells (replications) are plotted as thin semi-transparent lines, and medians are plotted as thick lines. (B) Plot of the fitted model values. Medians of the posterior distributions are plotted as thick lines, with credible intervals shown as progressively lighter-shaded areas. CI, credible interval.