Table 2.
Baseline characteristics of the study populations stratified by diabetes status.
| Group I nT2DM N = 264 | Group I T2DM n = 68 | Group II nT2DM N = 322 | Group II T2DM n = 103 | Group III nT2DM n = 267 | Group III T2DM n = 214 | |
|---|---|---|---|---|---|---|
| Age, years | 60 ± 11 | 60 ± 12 | 64 ± 10 | 65 ± 10 | 67 ± 10 | 67 ± 10 |
| Male sex (%) | 39 | 32 | 62 | 65 | 70 | 75 |
| T2DM duration (years) | N/A | 5 ± 4 | N/A | 8 ± 10 | N/A | 11 ± 8 |
| Hypertension (%) | 48 | 68 | 62 | 78 | 80 | 91 |
| Smoking (%) | 46 | 47 | 52 | 61 | 84 | 78 |
| Body mass index (kg/m²) | 27 ± 4 | 31 ± 6 | 27 ± 4 | 29 ± 5 | 26 ± 4 | 28 ± 4 |
| HbA1c (%) | 5.6 ± 0.4 | 7.1 ± 1.7 | 5.7 ± 0.3 | 7.2 ± 1.1 | 5.6 ± 0.4 | 7.1 ± 1.3 |
| Triglycerides (mg/dl) | 131 ± 78 | 166 ± 119 | 136 ± 85 | 182 ± 134 | 140 ± 86 | 180 ± 132 |
| Total cholesterol (mg/dl) | 213 ± 44 | 198 ± 47 | 210 ± 44 | 200 ± 45 | 185 ± 42 | 173 ± 49 |
| LDL-cholesterol (mg/dl) | 135 ± 36 | 119 ± 38 | 135 ± 38 | 124 ± 38 | 109 ± 35 | 98 ± 43 |
| HDL-cholesterol (mg/dl) | 60 ± 19 | 52 ± 16 | 57 ± 16 | 50 ± 14 | 56 ± 18 | 48 ± 16 |
| Systolic blood pressure (mm Hg) | 133 ± 19 | 139 ± 21 | 137 ± 19 | 140 ± 21 | 139 ± 22 | 142 ± 26 |
| Diastolic blood pressure (mm Hg) | 81 ± 10 | 84 ± 11 | 82 ± 10 | 82 ± 12 | 79 ± 11 | 79 ± 13 |
| Statin use (%) | 25 | 35 | 38 | 47 | 66 | 75 |
| ACE inhibitors / AT II RBA (%) | 26 | 47 | 39 | 51 | 46 | 70 |
| Beta receptor blocking agents (%) | 37 | 58 | 51 | 48 | 36 | 47 |
| Aspirin or clopidogrel (%) | 63 | 55 | 64 | 74 | 85 | 85 |
| eGFR-EPI (ml/min/1.73m2) | 83 | 80 | 74 | 68 | 72 | 68 |
| CKD (%) (EPI eGFR < 60 ml/min/1.73 m²) | 13 | 25 | 14 | 26 | 14 | 22 |
Data are shown for Group I, Group II and Group III as means ± SD if not denoted otherwise.
ACE angiotensin converting enzyme, ATII RBA angiotensin II receptor blocking agents, HbA1c hemoglobin A1c, HDL high density lipoprotein, LDL low density lipoprotein, T2DM type 2 diabetes mellitus, prior MI prior myocardial infarction, GFR-EPI glomerular filtration rate according to Chronic Kidney Disease Epidemiology Collaboration formula; CKD chronic kidney disease. To convert values for triglycerides to mmol/L multiply by 0.0113 and to convert values for total cholesterol, LDL cholesterol or HDL cholesterol to mmol multiply by 0.0259.