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. 2025 Jan 22;15:2792. doi: 10.1038/s41598-024-84985-x

Table 2.

Baseline characteristics of the study populations stratified by diabetes status.

Group I nT2DM N = 264 Group I T2DM n = 68 Group II nT2DM N = 322 Group II T2DM n = 103 Group III nT2DM n = 267 Group III T2DM n = 214
Age, years 60 ± 11 60 ± 12 64 ± 10 65 ± 10 67 ± 10 67 ± 10
Male sex (%) 39 32 62 65 70 75
T2DM duration (years) N/A 5 ± 4 N/A 8 ± 10 N/A 11 ± 8
Hypertension (%) 48 68 62 78 80 91
Smoking (%) 46 47 52 61 84 78
Body mass index (kg/m²) 27 ± 4 31 ± 6 27 ± 4 29 ± 5 26 ± 4 28 ± 4
HbA1c (%) 5.6 ± 0.4 7.1 ± 1.7 5.7 ± 0.3 7.2 ± 1.1 5.6 ± 0.4 7.1 ± 1.3
Triglycerides (mg/dl) 131 ± 78 166 ± 119 136 ± 85 182 ± 134 140 ± 86 180 ± 132
Total cholesterol (mg/dl) 213 ± 44 198 ± 47 210 ± 44 200 ± 45 185 ± 42 173 ± 49
LDL-cholesterol (mg/dl) 135 ± 36 119 ± 38 135 ± 38 124 ± 38 109 ± 35 98 ± 43
HDL-cholesterol (mg/dl) 60 ± 19 52 ± 16 57 ± 16 50 ± 14 56 ± 18 48 ± 16
Systolic blood pressure (mm Hg) 133 ± 19 139 ± 21 137 ± 19 140 ± 21 139 ± 22 142 ± 26
Diastolic blood pressure (mm Hg) 81 ± 10 84 ± 11 82 ± 10 82 ± 12 79 ± 11 79 ± 13
Statin use (%) 25 35 38 47 66 75
ACE inhibitors / AT II RBA (%) 26 47 39 51 46 70
Beta receptor blocking agents (%) 37 58 51 48 36 47
Aspirin or clopidogrel (%) 63 55 64 74 85 85
eGFR-EPI (ml/min/1.73m2) 83 80 74 68 72 68
CKD (%) (EPI eGFR < 60 ml/min/1.73 m²) 13 25 14 26 14 22

Data are shown for Group I, Group II and Group III as means ± SD if not denoted otherwise.

ACE angiotensin converting enzyme, ATII RBA angiotensin II receptor blocking agents, HbA1c hemoglobin A1c, HDL high density lipoprotein, LDL low density lipoprotein, T2DM type 2 diabetes mellitus, prior MI prior myocardial infarction, GFR-EPI glomerular filtration rate according to Chronic Kidney Disease Epidemiology Collaboration formula; CKD chronic kidney disease. To convert values for triglycerides to mmol/L multiply by 0.0113 and to convert values for total cholesterol, LDL cholesterol or HDL cholesterol to mmol multiply by 0.0259.