TABLE 2.

Definitions of colon histological damage scores.

Score	Crypt architecture	Crypt abscess	Inflammatory cell infiltration	Goblet cell depletion	Muscle thickness
0	Normal	Absent	Normal	Absent	Normal
1	Minor changes	Minor abscess	Minor increase in inflammatory cells	Minor loss of goblet cells	Minor increase in thickness
2	Moderate disruption in crypt architecture	Moderate abscess	Moderate inflammatory infiltrates	Moderate loss of goblet cells	Moderate increase in thickness
3	Severe damage, smooth epithelial lining	Severe crypt abscesses in epithelium	Significant inflammatory infiltrates	Severe loss/absence of goblet cells	Significant increase in thickness