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. 2025 Jan 14;29(3):141. doi: 10.3892/ol.2025.14887

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Copyright: © 2025 Hu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Correlation analysis of lnc-MAPKAPK5-AS1 expression and tumor microenvironment in HCC. (A) MK5-AS1 was positively linked with tumor immune cells infiltration levels of B cells, CD8⁺ T cells, CD4⁺ T cells, neutrophils and dendritic cells. (B) The relationships between MK5 and six types of cells of the immune system. (C) The box plot of 22 specific cells of the immune system exhibited by different groups by CIBERSORT. (D) Relationship between the expression of MK5-AS1 and 28 types of cells of the immune system in HCC by single sample Gene Set Enrichment Analysis. *P<0.05, **P<0.01 and ***P<0.001. HCC, hepatocellular carcinoma; TCGA-LIHC, The Cancer Genome Atlas Liver Hepatocellular Carcinoma; ns, not significant.