Table 1.

Haplotypes of 600 DRD4 exon 3 alleles

Allele	F	N	Haplotype	Allele	F	N	Haplotype
2R	0.088	55		6R	0.022	24
		43	1-4			16	1-2-3-2-3-4
		12	30-4*			2	1-2-6-5-2-20
3R	0.024	36				2	1-2-6-5-2-4
		16	1-7-4			1	1-2-14-17-2-4
		9	1-2-4			1	1-6-5-2-5-4
		4	1-11-33*			1	1-2-13-2-5-19
		3	1-9-4			1	24-6-5-2-5-4
		1	1-2-22	7R	0.192	199
		1	1-2-21			177	1-2-6-5-2-5-4
		1	1-2-31			5	1-2-6-5-2-5-19*
		1	1-2-32			3	1-2-6-5-2-3-4
4R	0.651	250				3	1-2-6-5-13-5-4*
		238	1-2-3-4			2	1-8-25-5-2-5-4
		3	1-2-14-4			2	1-2-3-5-2-5-4
		2	1-2-13-4			1	1-2-6-5-2-13-4
		2	1-2-12-4			1	1-2-29-17-2-5-4
		1	1-17-3-4			1	1-2-6-2-2-5-4
		1	1-9-12-4			1	1-8-25-5-2-3-4
		1	1-8-3-4			1	1-2-6-16-2-3-4
		1	1-10-3-4			1	1-2-6-5-2-14-4
		1	1-9-3-4			1	1-2-3-17-2-5-4
5R	0.016	27		8R	0.006	6
		12	1-3-2-3-4*			2	1-2-6-5-17-2-13-35*
		4	1-2-13-34-4*			1	1-2-6-5-2-2-5-4
		3	1-2-2-3-4			1	1-2-6-26-5-26-3-35
		2	1-2-6-5-4			1	1-2-6-26-5-26-3-4
		2	1-11-2-3-4			1	1-2-6-18-5-18-3-4
		1	1-3-2-14-4
		1	1-2-6-23-4	9R	<0.001	1	1-8-25-5-2-5-2-23-4
		1	1-2-3-9-4	10R	<0.001	1	1-2-15-6-2-6-5-2-5-4
		1	1-2-3-27-4	11R	<0.001	1	1-2-3-27-5-23-25-5-2-5-28

F, observed allele frequency in 2,836 chromosomes from 37 worldwide human populations (3,17); N, allele number identified by sequence analysis in this study (non-4R alleles were oversampled by 2–3-fold); haplotype, haplotypes are indicated using the repeat motif nomenclature proposed (Fig. 2). Alleles with adjacent asterisks indicate common variants found only in a single population sample (2R 30-4, Surui; 3R 1-11-33, Nasioi; 5R 1-3-2-3-4, Chinese; 5R 1-2-13-34-4, Biaka; 7R 1-2-6-5-2-5-19, Surui; 7R 1-2-6-5-13-5-4, Nasioi; 8R 1-2-6-5-17-2-13-35, Biaka). Alleles with a single representation by definition were found in only one population.