Table 2.
Cell-type specific expression patterns of transmembrane receptors and proteins in the human brain
| Neurons (nPTM) | Astrocytes (nPTM) | Microglial cells (nPTM) | Oligodendrocytes (nPTM) | Oligodendrocyte precursor cells (nPTM) | All cell types (nPTM) | |
|---|---|---|---|---|---|---|
| LRP1 | 37.77 (26.1–55) | 107.8 | 85.9 | 5.25 | 162.7 | 399.42 |
| LAG3 | 0.16 (0-0.9) | 0 | 0 | 0 | 0 | 0.16 |
| APLP1 | 53.05 (21.5-120.5) | 11.8 | 11.6 | 402.45 | 17.9 | 496.8 |
| TLR4 | 0.20 (0-1.3) | 48.3 | 25 | 0.3 | 7.1 | 80.9 |
| α3-NKA | 76.62 (17.9-159.9) | 8.7 | 8.1 | 11.05 | 13.7 | 69.28 |
| Integrin CD11b | 0.97 (0.5–2.3) | 0.6 | 39.4 | 0.4 | 2.8 | 44.17 |
| FcγRIIB | 0 | 0 | 0 | 0.05 | 0 | 0.05 |
| HSPG | 1.02 (0.3–4.8) | 3.4 | 15.2 | 3.25 | 2.4 | 25.27 |
| PrPc | 135.8 (73.1-229.7) | 113.9 | 56.4 | 133.4 | 89.1 | 528.6 |
| GPNMB | 0.63 (0-3.6) | 0.3 | 11.6 | 0.1 | 52.4 | 65.03 |
Cell-type specific expression levels of cell surface receptors and membrane proteins quantified in normalized protein transcript metric (nPTM). Data acquired from The Human Protein Atlas (proteinatlas.org) [56].