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. 2025 Jan 23;13:12. doi: 10.1186/s40364-025-00731-z

Table 2.

Association of NETs with diseases

Types of Diseases Names of Diseases The Role of NETs
Autoimmune Diseases SLE Promotes the formation of immune complexes[25, 26, 232]
Rheumatoid Arthritis Induces inflammation and joint damage [232, 233]
Infectious Diseases Bacterial Infections Combating bacterial infections [5]
Cardiovascular Diseases Stroke Promotes inflammatory response and exacerbates brain damage[234, 235]
Chronic Inflammatory Diseases Asthma and COPD Induces airway inflammation and tissue damage[4, 27]
Tumor Diseases Lung Cancer, Breast Cancer, Liver Cancer Promotes tumorigenesis, metastasis, and drug resistance[31, 42, 43, 48, 49]