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. 2025 Jan 22;23:40. doi: 10.1186/s12964-025-02041-1

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© The Author(s) 2025

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Fig. 4 — Linear discriminant analysis Effect Size (LEfSe) analysis of fecal metagenomics in the control (Atg5^+/+) and Atg5^−/− basophil transplanted MRL/lpr mice. (A, B) Cladograms and bar plots generated via LEfSe identify significantly different microbiota taxa between groups (Linear discriminant analysis > 2.5, P < 0.05). The diameter of each node in the cladograms is proportional to the relative abundance of the taxonomic unit. Red indicates taxa enriched in the Atg5^−/− group and green indicates taxa enriched in the control group