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. 2025 Jan 20;13:e18801. doi: 10.7717/peerj.18801

Table 2. The 2023 TBSRTC for adult population with the risk of malignancy (ROM) for each category.

Diagnostic category ROM, mean % (range) Usual management
Nondiagnostic 13 (5–20) Repeat FNA with ultrasound guidance
Benign 4 (2–7) Clinical and sonographic follow-up
Atypia of undetermined significance 22 (13–30) Repeat FNA, molecular testing, diagnostic lobectomy, or surveillance
Follicular neoplasm 30 (23–34) Molecular testing, diagnostic lobectomy
Suspicious for malignancy 74 (67–83) Molecular testing, lobectomy or near-total thyroidectomy
Malignant 97 (97–100) Lobectomy or near-total thyroidectomy

Note:

TBSRTC, Bethesda System for Reporting Thyroid Cytopathology. Adapted from Ali & VanderLaan (2023), Gharib et al. (2010).