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. 2001 Dec 18;99(1):407–412. doi: 10.1073/pnas.012587699

Figure 1.

Figure 1

Analyses of the plasma lipoproteins in hABCA1-Tg and C57BL/6 control mice maintained on the atherogenic diet. (A) The distribution of cholesterol after separation of the plasma lipoproteins present in pooled plasma from female C57BL/6 (■; n = 5) and hABCA1-Tg (○; n = 5) mice by FPLC. ApoA-I, apoA-II, and apoB present in FPLC fractions corresponding to VLDL (lanes 1), IDL/LDL (lanes 2), and HDL (lanes 3) elution volumes (15, 21, and 29 ml, respectively) were determined by immunoblot analysis (Inset). (B) Two microliters of plasma from C57BL/6 (C) and hABCA1-Tg (Tg) mice were analyzed by native agarose gel electrophoresis followed by staining with fat red B. (C) Detection of apoA-I by immunoblotting after two-dimensional gel electrophoresis of plasma from C57BL/6 and hABCA1-Tg mice.