Table 2.
Lipid, lipoprotein, and apolipoprotein analyses of hABCA1/ApoE-KO and ApoE-KO mice
| ApoE-KO (females) n = 12 3 mo | hABCA1 × ApoE-KO (females) n = 11 3 mo | ApoE-KO (males) n = 12 3 mo | hABCA1 × ApoE-KO (males) n = 13 3 mo | |
|---|---|---|---|---|
| TC | 616 ± 27 | 654 ± 32 | 809 ± 45 | 873 ± 55 |
| TG | 113 ± 6 | 117 ± 9 | 185 ± 13 | 187 ± 17 |
| PL | 331 ± 13 | 346 ± 15 | 478 ± 21 | 505 ± 32 |
| CE | 412 ± 20 | 454 ± 21 | 577 ± 33 | 617 ± 42 |
| FC | 204 ± 19 | 200 ± 17 | 231 ± 16 | 256 ± 19 |
| HDL-C | 12 ± 1 | 14 ± 1 | 27 ± 3 | 35 ± 4 |
| Non-HDL-C | 604 ± 27 | 640 ± 39 | 782 ± 45 | 838 ± 52 |
| ApoB* | 219.9 ± 7.4 | 201.9 ± 24.9 | 214.7 ± 12.3 | 211.3 ± 15.1 |
| ApoE* | — | — | — | — |
| Apo-AI* | 13.3 ± 2.2 | 13.9 ± 2.3 | 22.6 ± 6.4 | 26.7 ± 6.4 |
Data expressed as mean (mg/dl) ± SEM; P > 0.05, all.
*
n = 8.