Table 3.
Risk of drug resistance associated with SCN1A rs121917953 genotype, n (%)
|
Genotype
|
Drug-responsive, n = 52
|
Drug-resistant, n = 43
|
OR (95%CI)
|
P value
|
| TT | 18 (34.6) | 6 (13.9) | Reference | Reference |
| AT | 33 (63.4) | 36 (83.7) | 3.51 (1.256-3.826) | 0.017 |
| AA | 1 (1.9) | 1 (2.3) | 3.33 (0.180-61.686) | 0.419 |
OR: Odds ratio; 95%CI: 95% confidence interval. Reference polymorphism in regression analysis; P value was calculated using Binary Logistic regression analysis.