Table 2.
T-cell phenotyping of the studied groups.
| HTR (n = 12) | HC (n = 14) | p-value | |||
|---|---|---|---|---|---|
| CD4+T-cell | Total | %HLA-DR+CD38+ | 1.77 [1.19–2.04] | 1.31 [1.07–1.70] | 0.136 |
| %HLA-DR+ | 6.47 [3.51–7.5] | 3.25 [2.49–3.82] | 0.022 | ||
| %CD38+ | 25.7 [23.17–34.1] | 43.7 [36.1–49.5] | 0.010 | ||
| %CD25+ | 21.55 [18.45–33.5] | 11.2 [9.27–15] | 0.002 | ||
| %CD40L+ | 1.59 [0.61–2.98] | 1.15 [0.5–11.32] | 0.797 | ||
| %Treg | 1.1 [0.71–4.51] | 0.65 [0.39–1.11] | 0.088 | ||
| %CD45RA- | 77.3 [57.7–89.1] | 31 [25.25–35.8] | 0.001 | ||
| CD45RA- | %HLA-DR+CD38+ | 1.7 [1.43–2.55] | 1.39 [1.20–1.67] | 0.057 | |
| %HLA-DR+ | 6.31 [4.88–8.16] | 5.25 [4.34–5.49] | 0.324 | ||
| %CD38+ | 20.85 [12.65–26.12] | 19[14.12-23-67] | 0.758 | ||
| %CD25+ | 28.7 [23.55–36.37] | 20.9 [17.1–37.4] | 0.247 | ||
| %CD40L+ | 1.41 [0.24–2.58] | 0.94 [0.24–2.74] | 0.959 | ||
| %Treg | 1.27 [0.7–4.22] | 1.41 [0.97–2.19] | 0.818 | ||
| CD8+T-cell | Total | %HLA-DR+CD38+ | 3.95 [2.34–5.32] | 2.23 [1.32–3.16] | 0.007 |
| %HLA-DR+ | 7.08 [5.05–11.87] | 5.53 [3.76–6.24] | 0.045 | ||
| %CD38+ | 20.95 [13–28.1] | 15 [13.35–22.75] | 0.341 | ||
| %CD137+ | 1.75 [0.62–2.88] | 1.44 [1.16–1.76] | 0.537 | ||
| %CD45RA- | 55.4 [32.4–67.3] | 36.85 [22.87–42.57] | 0.060 | ||
| CD45RA- | %HLA-DR+CD38+ | 4.49 [2.64–7.48] | 2.58 [1.87–5.58] | 0.700 | |
| %HLA-DR+ | 8.48 [5.54–17.22] | 8.92 [6.42–12.42] | 0.643 | ||
| %CD38+ | 13.9 [8.44–18.42] | 11.85 [7.86–16.97] | 0.681 | ||
| %CD137+ | 2.25 [0.87–5.09] | 2.39 [1.79–3.23] | 0.877 |
Variables are expressed as medians and interquartile ranges [IQR]. Abbreviation: HTR, heart transplant recipients; HC, healthy controls. Mann-Whitney U test was used. P-value<0.05 are in bold and 0.05≤p-value<0.1 are in italics.