Table 3.
Systemic and intestinal CO2-derived parameters in sham, normal and increased blood flow groups
| Parameter | Group | Basal | Endotoxemia | |||
| 30 min | 60 min | 90 min | 120 min | |||
| Mixed venous – arterial PCO2 (mmHg) | Sham | 6 ± 2 | 6 ± 2 | 6 ± 2 | 6 ± 2 | 5 ± 2 |
| Normal | 7 ± 2 | 8 ± 2 | 7 ± 2 | 8 ± 3 | 8 ± 3† | |
| Increased | 6 ± 2 | 6 ± 3 | 7 ± 5 | 7 ± 4 | 4 ± 1‡ | |
| Mesenteric venous – arterial PCO2 (mmHg) | Sham | 6 ± 2 | 5 ± 2 | 5 ± 2 | 6 ± 2 | 5 ± 2 |
| Normal | 7 ± 2 | 8 ± 2 | 8 ± 3 | 10 ± 4 | 10 ± 2*† | |
| Increased | 8 ± 3 | 6 ± 2 | 8 ± 4 | 8 ± 3 | 6 ± 1*‡ | |
| Intramucosal – arterial PCO2 (mmHg) | Sham | 4 ± 4 | 5 ± 8 | 5 ± 8 | 5 ± 8 | 6 ± 9 |
| Normal | 7 ± 4 | 6 ± 5 | 12 ± 5 | 15 ± 6*‡ | 19 ± 4*‡ | |
| Increased | 5 ± 7 | 2 ± 9 | 7 ± 7 | 12 ± 8 | 9 ± 6† | |
| Systemic VCO2 (ml/min per kg) | Sham | 5.2 ± 1.9 | 4.5 ± 1.2 | 4.0 ± 1.5 | 4.7 ± 1.2 | 4.6 ± 1.8 |
| Normal | 6.0 ± 2.4 | 4.9 ± 1.4 | 4.9 ± 1.7 | 5.0 ± 1.3 | 5.0 ± 1.7 | |
| Increased | 6.5 ± 2.5 | 4.8 ± 2.4 | 6.1 ± 2.8 | 5.8 ± 2.3 | 5.8 ± 4.7 | |
| Intestinal VCO2 (ml/min per kg) | Sham | 36.7 ± 10.9 | 38.1 ± 11.3 | 34.0 ± 8.8 | 43.2 ± 10.6 | 36.7 ± 5.6 |
| Normal | 37.7 ± 10.9 | 35.3 ± 11.6 | 37.2 ± 13.7 | 41.8 ± 20.3 | 36.7 ± 16.2 | |
| Increased | 36.5 ± 21.8 | 35.3 ± 14.6 | 27.4 ± 9.4 | 35.8 ± 12.9 | 34.0 ± 7.4 | |
| Mixed venous blood capacity for transporting CO2 (ml/100 ml per mmHg) | Sham | 0.67 ± 0.12 | 0.59 ± 0.40 | 0.51 ± 0.11 | 0.61 ± 0.21 | 0.61 ± 0.13 |
| Normal | 0.62 ± 0.12 | 0.49 ± 0.12* | 0.55 ± 0.04* | 0.47 ± 0.09* | 0.44 ± 0.09*† | |
| Increased | 0.67 ± 0.24 | 0.38 ± 0.27* | 0.42 ± 0.24* | 0.45 ± 0.19* | 0.48 ± 0.12*† | |
| Mesenteric venous blood capacity for transporting CO2 (ml/100 ml per mmHg) | Sham | 1.14 ± 0.24 | 1.15 ± 0.32 | 1.22 ± 0.29 | 1.37 ± 0.22 | 1.28 ± 0.08 |
| Normal | 1.04 ± 0.22 | 0.99 ± 0.38 | 0.86 ± 0.24† | 0.78 ± 0.33*† | 0.76 ± 0.24*† | |
| Increased | 1.17 ± 0.45 | 0.85 ± 0.29 | 0.66 ± 0.27† | 0.81 ± 0.19† | 0.69 ± 0.18*† | |
* P < 0.05 versus basal. † P < 0.05 versus sham. ‡ P < 0.05 versus normal. Sham, sham group; normal, normal blood flow group; increased, increased blood flow group.