Table 1.
Sieving coefficient and clearance of myoglobin using conventional and super high-flux (SHF) continuous veno-venous hemofiltration in a patient with severe rhabdomyolysis secondary to serotonin syndrome
| Filter type | Ultrafiltration rate (l/hour) | Myoglobin concentration (μg/l) | Sieving coefficient (%) | Myoglobin removal (g/day) | Myoglobin clearance (ml/min) | ||
| Pre-filter | Post-filter | Ultrafiltrate | |||||
| Conventional (polysulphone) | 2 | >100,000 | >100,000 | 23003 | <0.23 | 1.1 | <8 |
| SHF | 2 | >100,000 | >100,000 | >100,000 | Unable to calculate | >4.8 | Unable to calculate |
| SHF | 3 | 100,000 | 68,776 | 60,912 | 0.722 | 4.4 | 30.5 |
| SHF | 4 | 91,058 | 64,587 | 53,527 | 0.688 | 5.1 | 39.2 |