Table 1. Baseline clinical and laboratory variables of included patients with SLE (n=166).
Variables | Values |
Age, years | 54.0 (11.0) |
Female | 161 (97.0) |
Postmenopause | 115/161 (71.4) |
Smoking history | 4 (2.4) |
BMI, kg/m2 | 21.65 (3.24) |
Duration of SLE, years | 16.2 (8.5) |
SLEDAI-2K score | 3.1 (3.2) |
C3, mg/dL | 87.8 (20.4) |
C4, mg/dL | 19.68 (9.03) |
Anti-DNA antibody, IU/mL | 12.657 (25.627) |
Calcium, mg/dL | 9.11 (0.46) |
25-Hydroxyvitamin D, ng/mL | 30.159 (14.572) |
T-score | |
Lumbar spine | −2.32 (0.91) |
≤−2.5 | 77 (46.4) |
Total hip | −1.90 (0.78) |
≤−2.5 | 28/160 (17.5) |
Femur neck | −2.34 (0.71) |
≤−2.5 | 41/104 (39.4) |
Areal BMD, g/cm2 | |
Lumbar spine | 0.7998 (0.0973) |
Total hip | 0.7192 (0.0880) |
Femur neck | 0.6079 (0.0730) |
Cumulative GC, mg | 19 159.28 (17 349.58) |
Duration of GC treatment, months | 197.6 (99.2) |
≤6 months | 4/161 (2.5) |
Concurrent GC, mg | 1480.56 (1475.81) |
Hydroxychloroquine use | 99 (59.6) |
Prior osteoporosis treatment | |
None | 121 (72.9) |
Bisphosphonates | 32 (19.3) |
SERMs | 13 (7.8) |
Bone turnover markers | |
CTx, ng/mL | 0.38939 (0.23692) |
P1NP, ng/mL | 48.70 (35.04) |
Data are shown as mean (standard deviationSD) or n (%).
BMDbone mineral densityBMIbody mass indexCTxC-telopeptide of collagen type 1GCglucocorticoidP1NPprocollagen 1 N-terminal propeptideSERMselective oestrogen receptor modulatorSLEDAI-2KSLE Disease Activity Index 2000