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. 2025 Jan 22;12(1):e001438. doi: 10.1136/lupus-2024-001438

Table 1. Baseline clinical and laboratory variables of included patients with SLE (n=166).

Variables Values
Age, years 54.0 (11.0)
Female 161 (97.0)
Postmenopause 115/161 (71.4)
Smoking history 4 (2.4)
BMI, kg/m2 21.65 (3.24)
Duration of SLE, years 16.2 (8.5)
SLEDAI-2K score 3.1 (3.2)
C3, mg/dL 87.8 (20.4)
C4, mg/dL 19.68 (9.03)
Anti-DNA antibody, IU/mL 12.657 (25.627)
Calcium, mg/dL 9.11 (0.46)
25-Hydroxyvitamin D, ng/mL 30.159 (14.572)
T-score
 Lumbar spine −2.32 (0.91)
 ≤−2.5 77 (46.4)
 Total hip −1.90 (0.78)
 ≤−2.5 28/160 (17.5)
 Femur neck −2.34 (0.71)
 ≤−2.5 41/104 (39.4)
Areal BMD, g/cm2
 Lumbar spine 0.7998 (0.0973)
 Total hip 0.7192 (0.0880)
 Femur neck 0.6079 (0.0730)
Cumulative GC, mg 19 159.28 (17 349.58)
Duration of GC treatment, months 197.6 (99.2)
 ≤6 months 4/161 (2.5)
Concurrent GC, mg 1480.56 (1475.81)
Hydroxychloroquine use 99 (59.6)
Prior osteoporosis treatment
 None 121 (72.9)
 Bisphosphonates 32 (19.3)
 SERMs 13 (7.8)
Bone turnover markers
 CTx, ng/mL 0.38939 (0.23692)
 P1NP, ng/mL 48.70 (35.04)

Data are shown as mean (standard deviationSD) or n (%).

BMDbone mineral densityBMIbody mass indexCTxC-telopeptide of collagen type 1GCglucocorticoidP1NPprocollagen 1 N-terminal propeptideSERMselective oestrogen receptor modulatorSLEDAI-2KSLE Disease Activity Index 2000