Table 2.
Functional redundancy of tbx-8 and tbx-9 is conserved in C. briggsae
Genotype | C. elegans | C. briggsae | ||||
Embryonic lethality | Morphological defect | Wild type larvae | Embryonic lethality | Morphological defect | Wild type larvae | |
tbx-8(RNAi) | 1% | 1% | 98% | 4% | 1% | 96% |
tbx-9(RNAi) | 1% | 1% | 98% | 3% | 2% | 95% |
tbx-8(RNAi);tbx-9(RNAi) | 48% | 52% | 0% | 39% | 46% | 15% |
RNAi was used for both genes in both species as no mutations are available for C. briggsae.