Table 1.
The characteristics of meningiomas in pediatric patients
| Clinical characteristics | [ALL] | No recurrence | Recurrence | P overall |
|---|---|---|---|---|
| N = 74 | N = 55 | N = 19 | ||
| Gender | 1.000 | |||
| Male | 34 (45.9%) | 25 (45.5%) | 9 (47.4%) | |
| Female | 40 (54.1%) | 30 (54.5%) | 10 (52.6%) | |
| Age (years) | Mean: 15.7 (Standard Deviation:4.33) | 15.6 (4.36) | 15.8 (4.37) | 0.884 |
| NF2-WNS | < 0.001 | |||
| No | 65 (87.8%) | 54 (98.2%) | 11 (57.9%) | |
| Yes | 9 (12.2%) | 1 (1.82%) | 8 (42.1%) | |
| Surgical history | 0.003 | |||
| de novo | 61 (82.4%) | 50 (90.9%) | 11 (57.9%) | |
| Recurrent | 13 (17.6%) | 5 (9.09%) | 8 (42.1%) | |
| Tumor location | 0.849 | |||
| Convexity | 29 (39.2%) | 21 (38.2%) | 8 (42.1%) | |
| Skull base | 23 (31.1%) | 16 (29.1%) | 7 (36.8%) | |
| Ventricular | 16 (21.6%) | 13 (23.6%) | 3 (15.8%) | |
| Parasagittal | 6 (8.11%) | 5 (9.09%) | 1 (5.26%) | |
| EOR | 0.012 | |||
| GTR | 56 (75.7%) | 46 (83.6%) | 10 (52.6%) | |
| STR | 18 (24.3%) | 9 (16.4%) | 9 (47.4%) | |
| WHO grade | 0.023 | |||
| Grade 1 | 61 (82.4%) | 49 (89.1%) | 12 (63.2%) | |
| Fibrous | 35 (42.3%) | 28(50.9%) | 7(36.8%) | |
| Meningothelial | 23 (31.1%) | 18(32.7%) | 5(26.3%) | |
| Translational | 2 (2.7%) | 2(3.6%) | 0(0.0%) | |
| Psammomatous | 1 (1.4%) | 1(1.8%) | 0(0.0%) | |
| Grade 2 | 12 (16.2%) | 6 (10.9%) | 6 (31.6%) | |
| Atypical | 10 (13.5%) | 5(9.1%) | 5(26.3%) | |
| Clear cell | 1(1.4%) | 0(0.0%) | 1(5.3%) | |
| Chordoid | 1(1.4%) | 1(1.8%) | 0(0.0%) | |
| Grade 3 | 1 (1.4%) | 0 (0.0%) | 1 (5.3%) | |
| Anaplastic | 1 (1.4%) | 0 (0.0%) | 1 (5.3%) | |
| Ki-67 (%) | Median: 3.00 [Quartiles:2.00;5.00] | 3.00 [2.00;5.00] | 3.00 [3.00;6.00] | 0.129 |
| PR: | 0.097 | |||
| Positive | 29 (39.2%) | 18 (32.7%) | 11 (57.9%) | Positive |
| Negative | 26 (35.1%) | 20 (36.4%) | 6 (31.6%) | |
| Weak positive | 19 (25.7%) | 17 (30.9%) | 2 (10.5%) |
NF2-SWN, NF2-related Schwannomatosis; EOR, extent of resection; GTR, gross total resection; STR, subtotal resection; PR, progesterone reception