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[Preprint]. 2025 Jan 31:2025.01.13.632865. Originally published 2025 Jan 13. [Version 2] doi: 10.1101/2025.01.13.632865

Table 2.

Relative abundances of investigated proteins between Zn-depleted and Zn-replete conditions (LFC = log2(Zn-depleted/Zn-replete)) and associated statistical measures.

Locus Tag Protein Name DDA DIA

LFC p-value Cohen’s d LFC p-value Cohen’s d

PA0781 ZnuD 9.477 0.031 4.528 6.692 0.04 3.964
PA0958 OprD 0.984 0.072 1.995 0.743 0.063 2.107
PA1922 - 5.341 0.038 3.961 4.141 0.128 2.048
PA1923 - 3.92 0.287 1.096 3.852 0.076 2.757
PA1925 - - - - 4.172 0.149 1.856
PA2435 - 2.87 0.052 2.955 2.903 0.121 2.098
PA2437 - 1.712 0.423 0.567 - - -
PA2438 HflC 4.945 0.011 6.284 3.601 0.053 3.366
PA2439 HflK 2.734 0.184 1.387 3.788 0.065 3.015
PA2505 OpdT −3.927 0.055 2.984 −2.787 0.181 1.639
PA2520 CzcA −4.406 0.13 1.94 −1.924 0.103 2.226
PA2521 CzcB −4.396 0.203 1.452 −3.476 0.112 2.221
PA2522 CzcC −2.583 0.041 3.268 - - -
PA2523 CzcR −1.446 0.423 0.517 - - -
PA2524 CzcS - - - 0.045 0.939 0.07
PA2911 - 5.212 0.12 2.081 5.728 0.094 2.475
PA2913 - 2.855 0.309 0.95 6.686 0.077 2.767
PA3438 FolE1 0.752 0.748 0.285 - - -
PA3527 PyrC1 −1.69 0.039 3.063 −0.396 0.56 0.52
PA3574.1 CopZ2 −1.255 0.054 2.207 −1.299 0.225 1.277
PA3601 RpmE2 1.39 0.423 0.505 4.841 0.044 3.714
PA3690 CadA/ZntA −6.113 0.013 7.029 −3.332 0.002 11.541
PA4022 HdhA −7.787 0.015 6.488 −2.000 0.064 2.127
PA4063 - 7.291 0.017 6.233 5.857 0.019 5.856
PA4064 - 4.302 0.361 0.911 - - -
PA4065 - 4.87 0.068 2.873 4.305 0.005 11.119
PA4066 - 1.39 0.423 0.505 3.202 0.132 1.993
PA4381 ColR −3.172 0.07 2.596 −4.548 0.362 0.958
PA4723 DksA −1.356 0.055 3.07 −0.03 0.969 0.035
PA4837 CntO/ZrmA 5.981 0.017 6.098 4.642 0.018 5.666
PA5049 RpmE −1.156 0.068 2.164 −2.966 0.093 2.462
PA5105 HutC −0.403 0.423 0.199 −0.581 0.406 0.759
PA5499 Zur −3.503 0.066 2.757 −0.181 0.703 0.344
PA5531 - 3.22 0.004 11.162 1.077 0.183 1.526
PA5534 - 3.478 0.423 0.743 4.255 0.056 3.309
PA5535 ZigA 6.304 0.045 3.662 5.838 0.084 2.639
PA5536 DksA2 1.712 0.423 0.567 0.867 0.413 0.746
PA5539 FolE2 3.214 0.212 1.318 - - -
PA5540 - 3.802 0.077 2.562 - - -
PA5541 PyrC2 0.434 0.423 0.212 - - -

P-values were determined through a heteroscedastic two-tailed t-test. Bolded values exceed desired statistical thresholds of p-value < 0.1 and effect size > 2.5. Missing values indicate the protein in question was not detected by that methodology.