Table 2. Gene mutation results after disease progression.

Gene	c.HGVS	p.HGVS	Functional region	Allele frequency
CARD11	c.455T>G	p.L152R	EX5	7.9%
MLL2	c.6440C>T	p.A2147V	EX31	4.5%
C15orf23	c.17C>T	p.A6V	EX1	4.2%
KRAS	Amplification	–	–	CN =6
TP53	c.809T>G	p.F270C	EX8	30.1%

c.HGVS, description of coding DNA (c.) variants by human genome variation society (HGVS); p.HGVS, description of protein (p.) variants by HGVS. CN, copy number.