REAGENT or RESOURCE	SOURCE	IDENTIFIER
Deposited data
HepG2 enhancers, RIE enhancers, positive and negative activity regions	Zenodo	https://zenodo.org/records/14502340
Experimental models: Cell lines
HepG2 (K3K27ac, H3K4me1, H3K27me3 and DNase)	Roadmap project	https://egg2.wustl.edu/roadmap/data/byFileType/peaks/consolidated/narrowPeak/
TFs ChIP-seq experiments in HepG2	ENCODE project	https://hgdownload.soe.ucsc.edu/goldenPath/hg19/encodeDCC/
Reporter assay QTLs (raQTLs) in HepG2	Database: GSE128325	https://www.nature.com/articles/s41588-019-0455-2
STARR-seq data in HepG2	ENCODE project ENCSR135NXN	https://genomebiology.biomedcentral.com/articles/10.1186/s13059-020-02194-x
Sharpr-MPRA data in HepG2	Database: GSE71279	https://www.nature.com/articles/nbt.3678
H3K27ac ChIP-seq peaks in rhesus liver tissues	ArrayExpress accession number E-MTAB-2633	https://www.sciencedirect.com/science/article/pii/S0092867415000070
Gene expression profile for developmental and adulthood stages in the human liver	ArrayExpress accession number E-MTAB-6814	https://www.nature.com/articles/s41586-019-1338-5
Files of HepG2 enhancers, RIE enhancers, PAR and NAR identified in this study are deposited in Zenodo	Zenodo	https://zenodo.org/records/14502340
Software and algorithms
TREDNet deep learning model	https://www.pnas.org/doi/10.1073/pnas.2206612120	https://zenodo.org/records/8161621
FIMO	https://meme-suite.org/meme/doc/fimo.html	MEME Suite