Fig. 2.
Blockade of TRPC3 decreased migration of TNBC cells BT-549. A Representative images showing the wound gap at 0 h, 16 h and 24 h after wound scratch in the wound healing assay under treatments of different concentrations of Pyr3, the pharmacological blocker of TRPC3. Scale bar: 500 μm. B Summarized data on the cell migration rates 24 h after wound scratch. Cell migration rates in the 3 μM and 10 μM Pyr3 treated groups were significantly decreased at 24 h when compared to DMSO control. Values are mean ± SEM (n = 3). * P < 0.05, ** P < 0.01, *** P < 0.001