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. 2002 Jun;13(6):2091–2105. doi: 10.1091/mbc.01-10-0500

Table 2.

Summary of in vivo requirements for events leading to Gin4 hyperphosphorylation

Event: In vivo requirements
Entry into mitosis Nap1 Cla4 Elm1 Shs1 Gin4 kinase activity Cdc28 kinase activity
Gin4-Nap1 Interaction  No  No  No  No  No  No
Gin4-Gin4 Interaction  Yes  No  No  N.D.  Yes  N.D.  N.D.
Gin4-Shs1 Interaction  Yes  No  No  No  Yes  Yes
Gin4-Cdc11 Interaction  Yes  Yes  Yes  Yes  Yes  Yes  Yes
Gin4 hyperphosphorylation  Yes  Yes  Yes  Yes  Yes  Yes  Yes