Table 2.
Summary of in vivo requirements for events leading to Gin4 hyperphosphorylation
| Event: | In vivo requirements
|
||||||
|---|---|---|---|---|---|---|---|
| Entry into mitosis | Nap1 | Cla4 | Elm1 | Shs1 | Gin4 kinase activity | Cdc28 kinase activity | |
| Gin4-Nap1 Interaction | No | — | No | No | No | No | No |
| Gin4-Gin4 Interaction | Yes | No | No | N.D. | Yes | N.D. | N.D. |
| Gin4-Shs1 Interaction | Yes | No | No | No | — | Yes | Yes |
| Gin4-Cdc11 Interaction | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| Gin4 hyperphosphorylation | Yes | Yes | Yes | Yes | Yes | Yes | Yes |