| 5-HT2A | 5-HT2A receptor (serotonin) |
| 5-HT2C | 5-HT2C receptor (serotonin) |
| 5-HT3 | 5-HT3 receptor (serotonin) |
| ACR | American College of Rheumatology |
| AC | Adenylyl cyclase |
| ACTH | Adrenocorticotropic hormone |
| ASIC | Acid-sensing ion channel |
| CAM | Complementary and alternative medicine |
| cAMP | Cyclic adenosine monophosphate |
| CB1 | Cannabinoid receptor 1 |
| CB2 | Cannabinoid receptor 2 |
| CBD | Cannabidiol |
| CD19 | Cluster of differentiation 19 |
| CD4 | Cluster of differentiation 4 |
| CGRP | Calcitonin gene-related peptide |
| CNS | Central Nervous System |
| D2 | Dopamine receptor D2 |
| DAG | Diacylglicerol |
| DOR | δ-opioid receptor |
| DYN | Dynorphin |
| ENK | Enkephalin |
| ERK | Extracellular signal-regulated kinase |
| EULAR | European Alliance of Associations for Rheumatology |
| FDA | Food and Drug Administration |
| FIQ | Fibromyalgia Impact Questionnaire |
| fMRI | Functional magnetic resonance imaging |
| GABA | γ-aminobutyric acid |
| GIRK | G protein-coupled inward rectifying potassium channel |
| GPCR | G protein-coupled receptor |
| HPA | Hypothalamic-pituitary-adrenal axis |
| IBS | Inflammatory bowel disease |
| IFN-γ | Interferon gamma |
| IL-10 | Interleukin 10 |
| IL-17 | Interleukin 17 |
| IL-6 | Interleukin 6 |
| IL-8 | Interleukin 8 |
| IP3 | Inositol triphosphate |
| KOR | κ-opioid receptor |
| LDN | Low-dose naltrexone |
| Leu-ENK | Leu-enkephalin |
| M1 | M1 phenotype macrophage |
| M2 | M2 phenotype macrophage |
| MAPK | Mitogen-activated protein kinase |
| Met-ENK | Met-enkephalin |
| MOR | μ-opioid receptor |
| MYT1L | Myelin transcription factor 1 like |
| NMDA | N-methyl-D-aspartate |
| NGF | Nerve growth factor |
| NRI | Selective noradrenaline reuptake inhibitor |
| NRXN3 | Neurexin 3 |
| OPRD1 | Opioid receptor delta 1 |
| OPRK1 | Opioid receptor kappa 1 |
| OPRM1 | Opioid receptor mu 1 |
| P2X3 | P2X purinergic receptor type 3 |
| PBMC | Peripheral blood mononuclear cell |
| PC | Prohormone convertase |
| PDYN | Prodynorphin |
| PENK | Proenkephalin |
| PKA | Protein kinase A |
| PLC | Phospholipase C |
| PNS | Peripheral Nervous System |
| POMC | Proopiomelanocortin |
| RCT | Randomized controlled trial |
| RLS | Restless legs syndrome |
| ROS | Reactive oxygen species |
| SLC6A4 | Solute carrier family 6 member 4 |
| SNP | Single nucleotide polymorphism |
| SNRI | Serotonin and noradrenaline reuptake inhibitor |
| SOD | Superoxide dismutase |
| SSRI | Selective serotonin reuptake inhibitor |
| TCA | Tricyclic antidepressant |
| TGF-β | Transforming growth factor beta |
| THC | Tetrahydrocannabinol |
| TNF-α | Tumor necrosis factor alpha |
| TRPV | Transient receptor potential vanilloid |
| TRPV1 | Transient receptor potential vanilloid 1 |
| TRPV2 | Transient receptor potential vanilloid 2 |
| VGCC | Voltage-gated calcium channel |
| α-MSH | α-melanocyte-stimulating hormone |
| β-END | β-endorphin |
| β-LPH | β-lipotropin |
| γ-LPH | γ-lipotropin |
| γ-MSH | γ-melanocyte-stimulating hormone |