Table 2.
Comparisons of frequencies of microcytosis (mean corpuscular volume or MCV <80 fL), macrocytosis (MCV ≥100 fL), blood hemoglobin and serum iron, vitamin B12, and folic acid deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody (GPCA) positivity between 588 oral lichen planus (OLP) patients and 588 healthy control subjects.
| Factor | Patient number (%) |
||
|---|---|---|---|
| OLP patients (n = 588) | Healthy control subjects (n = 588) | P-valuea (Chi-square test) | |
| Microcytosis (MCV <80 fL) | 78 (13.3) | 0 (0.0) | <0.001 |
| Macrocytosis (MCV ≥100 fL) | 36 (6.1) | 0 (0.0) | <0.001 |
| Hemoglobin deficiency (Men <13 g/dL, Women <12 g/dL) | 148 (25.2) | 0 (0.0) | <0.001 |
| Iron deficiency (<60 μg/dL) | 99 (16.8) | 0 (0.0) | <0.001 |
| Vitamin B12 deficiency (<200 pg/dL) | 60 (10.2) | 0 (0.0) | <0.001 |
| Folic acid deficiency (<4 ng/dL) | 7 (1.2) | 0 (0.0) | 0.023 |
| Hyperhomocysteinemia (>12.0 μM) | 124 (21.1) | 10 (1.7) | <0.001 |
| GPCA positivity | 139 (23.6) | 10 (1.7) | <0.001 |
a
Comparisons of frequencies of parameters between 588 OLP patients and 588 healthy control subjects by chi-square test.