Table 5:
Correlation between rs688 polymorphism in both CKD subgroups and the laboratory data
| Characteristics | CC (n = 33) | CT (n = 43) | TT (n = 24) | p-value |
|---|---|---|---|---|
| Age | 51.2 ± 12.8 | 51.2 ± 11.8 | 57 ± 9.5 | 0.068 |
| Years of dialysis | 7.4 ± 4.5 | 7.3 ± 3.7 | 7.7 ± 3.4 | 0.705 |
| Systolic blood pressure | 138.8 ± 14.0 | 138.5 ± 18.2 | 135.2 ± 12.9 | 0.773 |
| Diastolic blood pressure | 85.3 ± 11.7 | 84.3 ± 14.5 | 88.5 ± 10.1 | 0.413 |
| eGFR | 8.3 ± 1.9 | 7.4 ± 1.6 | 7.4 ± 2.1 | 0.063 |
| Gender | ||||
| Female | 8 (24.2%) | 16 (37.2%) | 10 (41.7%) | 0.329 |
| Male | 25 (75.8%) | 27 (62.8%) | 14 (58.3%) | |
| Hypertension | ||||
| No | 4 (12.1%) | 21 (48.8%) | 3 (12.5%) | <0.001 |
| Yes | 29 (87.9%) | 22 (51.2%) | 21 (87.5%) | |
| Cholesterol | 207.2 ± 46.2 | 238.1 ± 42.1 | 256.8 ± 47.8 | <0.001 |
| Triglyceride | 196.6 ± 68.3 | 228.4 ± 68.7 | 274.8 ± 74.6 | <0.001 |
| HDL | 38.5 ± 5.2 | 35.4 ± 5.4 | 32.9 ± 5.1 | <0.001 |
| LDL | 129.3 ± 39.6 | 156.9 ± 39.4 | 168.8 ± 46.1 | 0.002 |
| Creatinine | 6.9 ± 1.2 | 7.3 ± 1.1 | 7.2 ± 1.2 | 0.497 |
HDL: High-density lipoprotein; LDL: Low-density lipoprotein; eGFR: Estimated glomerular filtration rate. Bold indicates significant values, CC: Cytosine/cytosine genotype, TT: Thymine/thymine genotype, CT: Cytosine/thymine genotype.