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. 2024 Dec 27;13(1):35. doi: 10.3390/biomedicines13010035
ALS Amyotrophic lateral sclerosis
ALSFRS-R ALS functional rating scale-revised
ASC Adipose-derived stem cells
BBB Basso, Beattie, Bresnahan (motor strength test)
BDNF Brain-derived neurotrophic factor
BMSCs/BMD-MSCs Bone marrow-derived mesenchymal stem cells
BMD-MNCs Bone marrow-derived mononuclear cells
Cas9 CRISPR-associated protein 9
c-Myc Cellular myelocytomatosis proto-oncogene
CNS Central nervous system
CRISPR Clustered regularly interspaced palindromic repeats
CRISPR-Cas9 CRISPR-associated system for gene editing
CRISPR-GA CRISPR guide alignment
CRISPResso CRISPR analysis tool for editing efficiency
FVC Forced vital capacity
FDA Food and Drug Administration
ESC Embryonic stem cells
GABAA Gamma-aminobutyric acid type A
GDNF Glial cell-derived neurotrophic factor
GFAP Glial fibrillary acidic protein
HDR Homology-directed repair
hNSC Human neural stem cells
iNPCs Induced neural progenitor cells
iNSCs Induced neural stem cells
iPSCs Induced pluripotent stem cells
MCP-1 Monocyte chemoattractant protein 1
MRI Magnetic resonance imaging
mRNA Messenger RNA
NfL Neurofilament light
NHEJ Non-homologous end joining
NSCs Neural stem cells
PCR Polymerase chain reaction
PSC Pluripotent stem cell
p53 Tumour protein p53
qNSC Quiescent neural stem cells
SAM S-adenosylmethionine
SICI Short-interval intracortical inhibition
SCs Stem cells
sMNs Spinal motor neurons
SNVs Single nucleotide variants
SOD1 Superoxide dismutase 1
SOD1A4V SOD1 gene mutation (A4V)
TDP-43 TAR DNA-binding protein 43
TGF-β1 Transforming growth factor beta 1
TUJ1 Neuron-specific class III beta-tubulin
UC-MSCs Umbilical cord-derived mesenchymal stem cells
UCMSC-CM Umbilical cord mesenchymal stem cell-derived conditioned medium
WBC White blood cells
WJ-MSCs Wharton’s jelly mesenchymal stem cells