| ALS | Amyotrophic lateral sclerosis |
| ALSFRS-R | ALS functional rating scale-revised |
| ASC | Adipose-derived stem cells |
| BBB | Basso, Beattie, Bresnahan (motor strength test) |
| BDNF | Brain-derived neurotrophic factor |
| BMSCs/BMD-MSCs | Bone marrow-derived mesenchymal stem cells |
| BMD-MNCs | Bone marrow-derived mononuclear cells |
| Cas9 | CRISPR-associated protein 9 |
| c-Myc | Cellular myelocytomatosis proto-oncogene |
| CNS | Central nervous system |
| CRISPR | Clustered regularly interspaced palindromic repeats |
| CRISPR-Cas9 | CRISPR-associated system for gene editing |
| CRISPR-GA | CRISPR guide alignment |
| CRISPResso | CRISPR analysis tool for editing efficiency |
| FVC | Forced vital capacity |
| FDA | Food and Drug Administration |
| ESC | Embryonic stem cells |
| GABAA | Gamma-aminobutyric acid type A |
| GDNF | Glial cell-derived neurotrophic factor |
| GFAP | Glial fibrillary acidic protein |
| HDR | Homology-directed repair |
| hNSC | Human neural stem cells |
| iNPCs | Induced neural progenitor cells |
| iNSCs | Induced neural stem cells |
| iPSCs | Induced pluripotent stem cells |
| MCP-1 | Monocyte chemoattractant protein 1 |
| MRI | Magnetic resonance imaging |
| mRNA | Messenger RNA |
| NfL | Neurofilament light |
| NHEJ | Non-homologous end joining |
| NSCs | Neural stem cells |
| PCR | Polymerase chain reaction |
| PSC | Pluripotent stem cell |
| p53 | Tumour protein p53 |
| qNSC | Quiescent neural stem cells |
| SAM | S-adenosylmethionine |
| SICI | Short-interval intracortical inhibition |
| SCs | Stem cells |
| sMNs | Spinal motor neurons |
| SNVs | Single nucleotide variants |
| SOD1 | Superoxide dismutase 1 |
| SOD1A4V | SOD1 gene mutation (A4V) |
| TDP-43 | TAR DNA-binding protein 43 |
| TGF-β1 | Transforming growth factor beta 1 |
| TUJ1 | Neuron-specific class III beta-tubulin |
| UC-MSCs | Umbilical cord-derived mesenchymal stem cells |
| UCMSC-CM | Umbilical cord mesenchymal stem cell-derived conditioned medium |
| WBC | White blood cells |
| WJ-MSCs | Wharton’s jelly mesenchymal stem cells |