Table 3.
Number (%) of women with different histological classifications of endometrial tissue after 24-36 months of treatment with continuous combined hormone replacement therapy and on completion of 5 years of treatment or withdrawal from study
| Classification
|
Time endometrial sample taken
|
|
|---|---|---|
| At 24-36 months (n=465)*
|
On completion of 5 years of treatment or withdrawal (n=398)†
|
|
| Unassessable | 117 (25) | 92 (23) |
| Inactive or atrophic | 157 (34) | 185 (46) |
| Proliferative | 11 (2) | 8 (2) |
| Secretory | 162 (35) | 102 (26) |
| Pseudo-decidual | 8 (2) | 5 (1) |
| Menstrual | 0 | 0 |
| Complex hyperplasia | 0 | 0 |
| Atypical hyperplasia | 0 | 0 |
| Carcinoma | 0 | 0 |
| Other | 10 (2) | 6 (2) |
*
307 had received sequential hormone replacement therapy, 150 no previous hormone replacement therapy, and eight unopposed oestrogen.
†
263 had received sequential hormone replacement therapy, 127 no previous hormone replacement therapy, and eight unopposed oestrogen.