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. 2025 Jan 16;15(1):139. doi: 10.3390/biom15010139

Figure 1.

Figure 1

Expression vectors containing WT and variant MAVS (MAVS500) by agarose gel electrophoresis (a). Illustration of the rs3320008647 C > T change on the sequence analysis of MAVS500. The region marked with a red arrow shows the rs3320008647 C > T variant detected on MAVS500. Chromas version 2.6.6 was used to visualize the DNA sequences (b). The original agarose gel image is shown in Figure S1. The DNA sequencing result of the variant rat MAVS (MAVS500) obtained from the rat NBT-II cell line (c) and the DNA sequencing result of the WT rat MAVS obtained from NBT-II cells (d). The region corresponding to 7 aa at the beginning of Exon 3 (red frame) that was shown in the WT rat MAVS DNA sequence is absent in the MAVS500 DNA sequence. Chromas version 2.6.6 was used to visualize the DNA sequences. (e) Schematic view of WT rat MAVS and MAVS500 splicing.