Table I.

DNA microarray analysis of changes in gene expression upon mutation of the hik34 gene in Synechocystis

Genes whose expression was induced (induction factor >3.0) by heat shock at 44°C for 20 min are underlined. The values are averages of results of three independent experiments. Genes marked by the same Greek letter are located in tandem on the Synechocystis genome.

Gene ID	Gene	Product	Δhik34/Wild Type
Genes whose expression was enhanced by mutation of Hik34
sll0430	htpG	HSP 90	2.94 ± 0.19
slr1634		Protein of unknown function	2.72 ± 1.05
slr1808	hemA	tRNA-Gln reductase	2.25 ± 0.72
slr2075α	groES	10-kD chaperonin	1.94 ± 0.75
sll1579	cpcC	Phycocyanin-associated linker	1.81 ± 0.67
slr2076α	groEL1	60-kD chaperonin 1	1.70 ± 0.50
sll1453	nrtD	Component of nitrate transporter	1.69 ± 0.41
sll1324	atpF	Subunit-β of ATP synthase	1.66 ± 0.40
ssl3044		Ferredoxin-like protein	1.55 ± 0.32
slr0927	psbD2	D2 protein of photosystem II	1.54 ± 0.58
sll1867	psbA3	D1 protein of photosystem II	1.50 ± 0.48
sll1514	hspA	Small HSP	1.50 ± 0.32
Genes whose expression was repressed by mutation of Hik34
slr1704		Protein of unknown function	0.39 ± 0.19
sll0788β		Protein of unknown function	0.45 ± 0.08
sll0789β	rre34	Rre34	0.46 ± 0.05
sll0856	sigE	RNA polymerase σ-E factor	0.47 ± 0.16
sll0790β	hik31	His kinase 31	0.48 ± 0.01
sll1336		Protein of unknown function	0.53 ± 0.06
sll1070	tktA	Transketolase	0.59 ± 0.06
slr1198		Antioxidant protein	0.61 ± 0.13
ssr1375		Protein of unknown function	0.62 ± 0.12
ssl2245		Protein of unknown function	0.62 ± 0.04
slr1261		Protein of unknown function	0.64 ± 0.09