Table 4.
Correlating cognitive function in SLE patients to absolute volumes of aHC, pHC, HC, and BA35
| Cognitive function | Region of interest | SLE patients | Cognitive function | Region of interest | SLE patients | ||
|---|---|---|---|---|---|---|---|
| Pearson’s partial correlation coefficient | p-value | Pearson’s partial correlation coefficient | p-value | ||||
| Visual memory (VisuM) | aHC | −0.002 | 0.98 | Complex attention (CompA) | aHC | 0.16 | 0.19 |
| pHC | 0.007 | 0.95 | pHC | 0.06 | 0.63 | ||
| HC | 0.003 | 0.98 | HC | 0.14 | 0.26 | ||
| BA35 | −0.009 | 0.94 | BA35 | 0.20 | 0.10 | ||
| Processing speed (ProcS) | aHC | 0.19 | 0.11 | Executive function (ExecF) | aHC | 0.08 | 0.50 |
| pHC | 0.09 | 0.46 | pHC | 0.004 | 0.97 | ||
| HC | 0.18 | 0.15 | HC | 0.05 | 0.65 | ||
| BA35 | 0.21 | 0.09 | BA35 | 0.14 | 0.24 | ||
| Simple attention (SimpA1) | aHC | 0.13 | 0.44 | MADRS-S2 | aHC | 0.07 | 0.47 |
| pHC | 0.28 | 0.10 | pHC | −0.04 | 0.67 | ||
| HC | 0.28 | 0.10 | HC | 0.02 | 0.79 | ||
| BA35 | 0.08 | 0.63 | BA35 | 0.04 | 0.69 | ||
Abbreviations MADRS-S: Montgomery-Åsberg depression rating scale, self-reported; aHC/pHC: anterior/posterior hippocampus; BA35: Brodmann area 35
1SimpA has missing values in 31 SLE patients and 2 HI
2Partial correlations between MADRS-S and volume were not adjusted for education level