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. Author manuscript; available in PMC: 2026 Mar 1.
Published in final edited form as: Dev Biol. 2024 Dec 10;519:30–37. doi: 10.1016/j.ydbio.2024.12.003

Figure 2: Septal defects.

Figure 2:

A-E. H&E serial cross-sections through hearts representing different heart defects. Corresponding diagrams of the hearts show levels for each section. Sections within a column come from a single heart. Sections from five hearts are shown. ‘OFT valves’ refer to the semilunar valves. Blue dashed lines show communication between left and right sides of the heart that should not be present at this stage of development. A. Wild type. B. Partial interventricular communication. C-D. DORV. E. Common Arterial Trunk (PTA). F. Incidence of embryos with abnormal OFT septation. G. Incidence of embryos with full or partial interventricular communication. H. Frequency of defects affecting septation. A = aorta, P = pulmonary trunk, OFT = outflow tract, LA = left atrium, RA = right atrium, LV = left ventricle, RV = right ventricle, Pr = pulmonary root, Ar = Aortic root.