Table 3. Cox proportional hazard analysis.

	RFS			OS
	HR	95% CI	p value	HR	95% CI	p value
pStage > II	1.68	1.00–2.83	0.052	1.84	0.85–3.98	0.123
EGFR mutation	1.79	1.02–3.15	0.041	1.39	0.65–3.00	0.398
Lymphatic invasion	2.60	1.49–4.53	<0.001	2.21	1.00–4.91	0.051
Vascular invasion	1.16	0.65–2.09	0.616	1.32	0.57–3.06	0.520
Micropapillary	1.57	0.84–2.91	0.157	1.64	0.63–4.28	0.311
Solid	1.40	0.79–2.49	0.246	0.94	0.43–2.05	0.878

RFS: recurrence-free survival; OS: overall survival; HR: hazard ratio; CI: confidence interval; pStage: pathological stage; EGFR: epidermal growth factor receptor