Table 4.
The intra- and interassay accuracies and precisions for analysis of Pz-1 from spiked rat plasma.
| Intraassay | Interassay | |||||||
|---|---|---|---|---|---|---|---|---|
| Conc (nM) | Accuracy (100±x%)a | Precision (%)b | Accuracy (100±%)a | Precision (%)b | ||||
| Day 1 | Day 2 | Day 3 | Day 1 | Day 2 | Day 3 | |||
| 3 (LLOQ) | 11 | 11 | 3.1 | 2.8 | 6.0 | 10.7 | 8.4 | <6.6 |
| 5 (Low) | 9 | 4 | 2 | 10.9 | 7.11 | 14.7 | 5 | <10.8 |
| 15 (Med) | 9 | 8 | 10 | 15.4 | 7.06 | 5.62 | 9 | <9.2 |
| 30 (High) | 4 | 12 | 9.6 | 11.9 | 12.1 | 11.7 | 2.1 | <11.8 |
a
QC method validation (N = 5).
b
Mean of three different days of QC method validation (N = 15).