Table 2.
Treatment-related adverse events for the immunotherapies in AML
| Drug | Major toxicities |
|---|---|
| Talacotuzumab (CSL362) | Myelosuppression |
| Evaporcept (ALX148) | Urticaria, neutropenia, abdominal disconfort |
| Cusatuzumab | Neutropenia, Lung infection |
| Lintuzumab | Myelosuppression |
| Daratumumab, Isatuximab | Infusion site reaction, edema, neutropenia |
| Gemtuzumab Ozogamicin | Veno-occlusive disease, Hepatotoxicity |
| Gilteritinib | Ventricular arrythmia, myelosuppression |
| Vadastuximab talirine | Venous Thrombosis, myelosuppression |
| Immune Checkpoint Inhibitors | Immune-related adverse events (gastrointestinal, endocrine, dermatologic, neurotoxicity and pulmonary toxicity) |
| Chimeric antigen receptor T-cell therapies | CRS, ICANS |