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. 2025 Jan 13;15:1512543. doi: 10.3389/fimmu.2024.1512543

Table 7.

Total concentration of each chemical in GNRs, reported oral LOD50 for each chemical and the highest i.v. (intervenes) dose of GNRs tested in for rat model.

Chemical Name Total concentration in Sona Nanotech Inc.™ GNRs solution Oral LD50 (Rat) Values Highest tolerated dose of Sona Nanotech Inc.™ GNRs tested in Rat model
PEG 45-65mg/L >4 g/Kg1 5mL/Kg
Surfactant 1 20-35mg/L 71 mg/kg
Surfactant 2 60-72mg/L 410 mg/kg2

1Thiol PEG are reported to have variable LOD and 4g/kg is the lowest reported value.

2LOD value for surfactant 2 is unavailable and reported value is for CTAB.