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. 2025 Jan 8;28(1):pyaf001. doi: 10.1093/ijnp/pyaf001

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© The Author(s) 2025. Published by Oxford University Press on behalf of CINP.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Time course of the blood plasma profiles of DMT and harmine (first row), DMT-N-oxide and harmol (second row), and NMT and 3-IAA (third row) after the administration of harmine + placebo (first column) and DMT + harmine (second and third column). The lines indicate mean analyte concentrations (displayed in ng/mL), and shades indicate the SEM. The x-axis displays the time (minutes) in relation to the start of the intranasal placebo/DMT administration at time point 0. 3-IAA, indole-3-acetic acid; DMT, N,N-dimethyltryptamine.