Table 3.

Univariate and multivariate survival analysis of ACC patients for cancer-specific survival.

Characteristic	Univariate analysis			Multivariate analysis
	HR	95% CI	P value	HR	95% CI	P value
Age (yr)	1.010	1.002–1.018	.017
Sex
Male	Reference
Female	0.907	0.802–1.026	.907
Marital status
Married	Reference
Unknown/Unmarried	0.981	0.867–1.110	.762
Median income
<$7500	Reference
≥$75,000	1.007	0.884–1.147	.918
Race
White	Reference
Black	0.745	0.520–1.065	.107
Others	1.185	0.855–1.642	.308
Laterality
Left	Reference
Right	0.930	0.824–1.050	.243
T stage
pT1–2	Reference			Reference
pT3–4	2.330	1.816–2.990	<.001	2.060	1.589–2.671	<.001
N stage
pN0	Reference
pN1	2.728	1.933–3.850	<.001
Surgery performed
Yes	Reference			Reference
No	2.341	2.032–2.696	<.001	3.944	2.885–5.390	<.001
Radiation
Yes	Reference
No	1.151	0.983–1.348	.081	1.507	1.075–2.114	.017
Chemotherapy
Yes	Reference
No	0.822	0.727–0.929	.002
Bone metastases
Yes	Reference			Reference
No	0.615	0.489–0.773	<.001	0.427	0.259–0.704	.001
Liver metastases
Yes	Reference			Reference
No	0.458	0.394–0.533	<.001	0.525	0.372–0.740	<.001
Lung metastases
Yes	Reference
No	0.551	0.481–0.633	<.001

ACC = adrenocortical carcinoma, CI = confidence interval, HR = hazard ratio.