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. 1971 Oct;124(4):695–700. doi: 10.1042/bj1240695

Synthesis and enzymic hydroxylation of protocollagen model peptide containing a hydroxyproline residue

Y Kikuchi 1, D Fujimoto 1, N Tamiya 1
PMCID: PMC1177246  PMID: 5167191

Abstract

1. Two protocollagen model peptides, Z-Gly-Pro-Hyp-Gly-(Pro-Pro-Gly)5 (Z, benzyloxycarbonyl) and AOC-(Pro-Pro-Gly)6 (AOC, tert.-pentyloxycarbonyl), were synthesized and hydroxylated with protocollagen proline hydroxylase. 2. The two model peptides were hydroxylated equally. The results suggest that the hydroxyl group of hydroxyproline contained in the N-terminal region of the peptide has no effect on the enzymic hydroxylation of the model peptide.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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